Elvin E. Brown
Term Assistant Professor of Biological Sciences
Ph.D. University of Alaska Fairbanks
Office: CPSB 302C
BIOL A102 Introductory Biology Research Interests:
Development of the vertebrate embryo requires exquisite regulation of genes and cellular processes. Working in the laboratory of Dr. Jocelyn Krebs, I am conducting loss of function experiments to study how an enzyme complex known as CHRAC regulates genes in development by altering the chromosome structure around them. Collaborating with investigators in the Krebs lab and in laboratories in other institutions I am characterizing the role of CHRAC in morphogenesis and in gene regulation in frog embryos. I use numerous techniques of molecular biology and computational molecular biology in this research.
- B.S. Genetics, University of California, Berkeley, 1975.
- Ph.D. Biochemistry and Molecular Biology, University of Alaska, Fairbanks, 2010.
- Smith, R.E. and Brown, E.E. (1998). The significance of hypersialylation of Dipeptidyl Peptidase IV (CD26) in the inhibition of its activity by Tat and other cationic peptides. Aids Research and Human Retroviruses 14:851-868.
- Brown, E.E., Malakar, S., and Krebs, J.E. (2007). How many remodelers does it take to make a brain? Diverse and cooperative roles of ATP-dependent chromatin-remodeling complexes in development. Biochemistry and Cell Biology 85:444-462.
Brown, E.E. and J.E. Krebs (2004). SWI2/SNF2 homologs in Xenopus. Biochemistry and Cell Biology 82:517.
Brown, E.E., J.J. Henry, and J.E. Krebs (2009). Developmental roles of the histone fold protein CHRAC17 in Xenopus. Biochemistry and Cell Biology 87:821.