IACUC Regulations

UAA Animal Welfare Assurance

Click here to download the University's Assurance of Compliance with Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals. This document was reviewed and approved by the Office of Laboratory Animal Welfare (OLAW) in January 2012.

Federal Regulations

U.S. GOVERNMENT PRINCIPLES FOR THE UTILIZATION AND CARE OF VERTEBRATE ANIMALS USED IN TESTING, RESEARCH, AND TRAINING
These 9 principles provide the basis for all the regulations and guidelines governing the care and use of vertebrate animals.

Animal Welfare Act and Regulations
Links to the Animal Welfare Act, various amendments and related documents as well as the Animal Welfare Regulations. Oversight is by Animal Care, USDA. The regulations will never qualify as exciting reading, but this is the primary document that addresses use of animals in research. For the purposes of these regulations, the following definition of an animal applies (see the regs):

Animal means any live or dead dog, cat, nonhuman primate, guinea pig, hamster, rabbit, or any other warmblooded animal, which is being used, or is intended for use for research, teaching, testing, experimentation, or exhibition purposes, or as a pet. This term excludes: Birds, rats of the genus Rattus and mice of the genus Mus bred for use in research, and horses not used for research purposes and other farm animals, such as, but not limited to livestock or poultry, used or intended for use as food or fiber, or livestock or poultry used or intended for use for improving animal nutrition, breeding, management, or production efficiency, or for improving the quality of food or fiber.

With respect to a dog, the term means all dogs, including those used for hunting, security, or breeding purposes. In addition to research facilities these regulations also apply to exhibitors, transport of animals, and dealers. Regulatory agency is the United States Department of Agriculture (USDA). Title 9 Code of Federal Regulations.

Health Research Extension Act of 1985 (Public Law 99-158)
This Act instructed the Secretary of Health and Human Services, acting through the Director of NIH, to establish guidelines for the proper care of animals to be used in biomedical and behavioral research.

Guide for the Care and Use of Laboratory Animals (1996)
The Guide (8th edition) has been recently updated by a committee of experts, after considering input from laboratory animal communities and the public at large. A free PDF copy of the 8th edition is available here.

The Guide provides basic information on housing, care, physical plant, and veterinary care for laboratory animals. The Guide is one of the major resources for animal care and applies to conventional lab animals as well as the captive wildlife commonly held at UAA.

2007 Report of the American Veterinary Medical Association Guidelines on Euthanasia
This report is formerly known as the 2000 Report of the AVMA Panel on Euthanasia. These are the most recent guidelines governing humane euthanasia. It is extremely important to review this document if euthanasia is a component of your research. Those of you working with wildlife should also consult this Report. There is a section on Euthanasia of Nonconventional Species: Zoo, Wild, Aquatic, and Ectothermic Animals. Those of you conducting field research may find contradictions between this Report and the Field Research Guidelines. For example the use of chloroform is not recommended by the AVMA Panel because of human health concerns, however its use is supported in the Acceptable Field Methods of Mammalogy. Also consider the following notices from the 2000 report:

  • The guidelines are in no way intended to be used for human lethal injection.
  • The application of a barbiturate, paralyzing agent, and potassium chloride delivered in separate syringes or stages is not cited in the report.
  • The report never mentions pancuronium bromide or Pavulon, the paralyzing agents used in human lethal injection.