Dr. McCoy

Dr. Mark R. McCoy

Assistant Professor of Chemistry
Office: CPSB 302 G
Phone: (907) 786-1260
Email: mrmccoy@uaa.alaska.edu

Biography

Dr. McCoy was born and raised in Anchorage Alaska and completed his undergraduate chemistry degree here at UAA. He left for his graduate education at UC Davis and came back to Alaska to teach here at UAA in 2012.

Education

Ph.D. in Chemistry, University of California, Davis, 2008

B.S. in Chemistry, University of Alaska Anchorage, Anchorage, 2003

Career History


8/12 - present University of Alaska Anchorage
Department of Chemistry
Assistant Professor of Chemistry

11/10 - 5/12 University of California, Davis
Department of Environmental Toxicology
Guest Lecturer

12/08 - 5/12 University of California, Davis
Department of Entomology
Post-doctoral Research Associate

01/04 - 10/08 University of California, Davis
Department of Chemistry
Research Assistant

10/03 - 12/04 University of California, Davis
Department of Chemistry
Teaching Assistant

9/02 - 8/03 University of Alaska Anchorage
Department of Chemistry
Research Assistant

6/02 - 12/02 University of Alaska Anchorage
Departments of Chemistry and Biology
Adjunct Faculty

Teaching Responsibilites

General Chemistry (CHEM 105 - 106) This course covers all the basic concepts of chemistry. The concepts at this level can be reinforced nicely through use of examples which relate chemistry to environmental, health and industrial problems. (Last taught, Spring 2013)

Quantitative Analysis (CHEM 312) This course covers chemical equilibria, acid-base titrations, statistical methods, chromatography, etc. The course is heavily laboratory oriented with six hours of lab each week. (Last taught, Fall 2012)

Research Interests

 My interests are bioanalytical chemistry with a focus on development of immunoassay biosensors. My lab focuses on the following areas: organic synthesis of small molecule haptens and antigens for antibody development, the development of antibodies through recombinant and non-recombinant means, and validation of immunoassay results through traditional instrumental methods. Current targets that I am focused on include Vitamin D metabolites and the picolinic acid family of herbicides.

Publications

  1. Ranganathan A, Paradise GA, Hansen CA, McCoy MR, Gee SJ, Zhong P, Chang D, Hammock BD. Indirect homologous competitive enzyme-linked immunosorbent assay for the detection of a class of glycosylated dihydrochalcones. J. Agric. Food Chem. 2013, 61, 6964-6970. PMID: 23767873.
  2. McCoy MR, Yang Z, Fu X, Ahn KC, Gee SJ, Bom DC, Zhong P, Chang D, Hammock BD. Monitoring of total type II pyrethroid pesticides in citrus oils and water by converting to a common product, 3-phenoxybenzoic acid. J. Agric. Food Chem. 2012, 60, 5065-5070. PMID: 22486225.
  3. Kim HJ, McCoy MR, Majkova Z, Dechant JE, Gee SJ, Tabares-da Rosa S, Gonzalez-Sapienza GG, Hammock BD. Isolation of Alpaca Anti-Hapten Heavy Chain Single Domain Antibodies for Development of Sensitive Immunoassay. Anal. Chem. 2012, 84, 1165-1171. PMID: 22148739.
  4. Zolkowska D, Banks CN, Dhir A, Inceoglu B, Sanborn JR, McCoy MR, Bruun DA, Hammock BD, Lein PJ, and Rogawski MA. Characterization of Seizures Induced by Acute and Repeated Exposure to Tetramethylenedisulfotetramine. J. Pharmacol. Exp. Ther., 2012, 341, 435-446. PMID: 22328574.
  5. Kim HJ, McCoy MR, Gee SJ, Gonzalez-Sapienza GG, Hammock BD. Noncompetitive phage anti-immunocomplex real-time polymerase chain reaction for sensitive detection of small molecules. (2011) Anal. Chem. 83, 246-53. PMID: 21141939
  6. Ahn KC, Kim HJ, McCoy MR, Gee SJ, Hammock BD. Immunoassays and biosensors for monitoring environmental and human exposure to pyrethroid insecticides. (2011) J. Agric. Food Chem. 59, 2792-802 PMID: 21105656
  7. Wei LH, Olafsen T, Radu C, Hildebrandt IJ, McCoy MR, Phelps ME, Meares C, Wu AM, Czernin J, Weber WA. Engineered antibody fragments with infinite affinity as reporter genes for PET imaging. (2008) J. Nucl. Med., 49, 1828-35 PMID: 18927335
  8. Miao Z, McCoy MR, Singh DD, Barrios B, Hsu OL, Cheal SM, and Meares CF. Cysteinylated protein as reactive disulfide: an alternative route to affinity labeling. (2008) Bioconjug Chem., 1, 15-19 PMID: 18062660
  9. Dodds ED, McCoy MR, Rea LD, Kennish JM, Proton Transfer Chemical Ionization Mass Spectrometry of Fatty Acid Methyl Esters Separated by Gas Chromatography: Quantitative Aspects. (2005) Eur. J. Lipid Sci Technol. 107, 560-564 DOI: 10.1002/ejlt.200501174
  10. Dodds ED, McCoy MR, Rea LD, Kennish JM. Gas Chromatographic Quantification of Fatty Acid Methyl Esters: Flame Ionization Detection vs. Electron Impact Mass Spectrometry. (2005) Lipids, 40, 419-428 PMID: 16028722
  11. Dodds ED, McCoy MR, Geldenhuys A, Rea LD, Kennish JM. Microscale Recovery of Total Lipids from Fish Tissue by Accelerated Solvent Extraction. (2004) JAOCS, 81, 835-840