Dr. Colin M. McGill

Assistant Professor of Chemistry
Office: CPSB 302D
Phone: (907) 786-1271
Email: cmmcgill@uaa.alaska.edu

Biography

 Dr. McGill was born and raised in Alaska.  He is still here.

Education

Ph.D. in Biochemistry and Molecular Biology, University of Alaska Fairbanks, 2010.

M.S. in Chemistry, University of Alaska Fairbanks, 2005.

B.S. in Chemistry, University of Alaska Fairbanks, 2001.

Teaching Responsibilites

Organic Chemistry I (Chem 321) – This course investigates the chemistry of carbon compounds including alkanes, alkenes, alkynes, alkyl halides, and arenes. Discussion includes physical properties, nomenclature, synthesis, reactions, reaction mechanisms, and stereochemistry of these compounds.

Organic Chemistry II (Chem 322) – This course is a continuation of Chem 321, including the study of spectroscopic techniques for structure determination, and the chemistry of alcohols, ethers, epoxides, thiols, sulfides, carbonyl compounds, amines, carbohydrates, and amino acids. Emphasis is placed on nomenclature, physical properties, synthetic methods, and reaction mechanisms.

Organic Chemistry Laboratory (Chem 323L) – This course is a practical implementation of the theory learned in Chem 321 and 322. Purification techniques, spectroscopic methods, and synthetic methods of organic compounds will be taught.

Biochemistry I (Chem 441) - This course is a study of the structure and function of amino acids, proteins, carbohydrates, nucleic acids, lipids and membranes.

Biochemistry II (Chem 442) – This course is a study of the bioenergetics and the metabolic pathways of amino acids, proteins, carbohydrates, nucleic acids, and lipids.

Biochemistry Laboratory (Chem 443L) – This is a laboratory course designed to provide instruction in modern biochemical laboratory techniques, emphasizing experimental design and data analysis.

Research Interests

Some of Dr. McGill's research interests are:

- Identification and characterization of biologically relevant secondary metabolites in Alaskan ethnobotanicals.

- Investigation of the roles of specific compounds found in the Alaskan bog blueberry for their impact on inflammation, neuroprotection, and memory.

- Investigation of the effects of Devil's club on inflammatory processes.

Publications

  1. C.M. McGill, K.E. Swearingen, K.L. Drew, B.T. Rasley, T.K. Green “Reaction of Napthalene-2,3-dialdehyde with Cyanide; A Unique Oxidative Condensation Product.” Journal of Heterocyclic Chemistry 2005, 42(4), 475-481.
  2. S.J. Gustafson, B.M. Barth, C.M. McGill, T.P. Clausen, T.B. Kuhn “Wild Alaskan Blueberry Extracts Inhibit a Magnesium-Dependent Neutral Sphingomyelinase Activity in Neurons Exposed to TNFα.” Current Topics Neutr. Res. 2007, 5(4), 183-188.
  3. S.J. Gustafson, K.L. Dunlap, C.M. McGill, T.B Kuhn “A Nonpolar Blueberry Fraction Blunts NADPH Oxidase Activation in Neuronal Cells Exposed to Tumor Necrosis Factor-α.” Oxidative Medicine and Cellular Longevity Vol. 2012, Arcticle ID 768101.