Mass Spectrometry

Triple Quad

Ion Trap

The primary function of an MS is to determine the mass of a compound. Also, through fragmentation of the parent compound, information about the chemical structure can be deduced.

Mass Spectrometers are equipped with different sources in an effort to generate ions depending on the class of the compound.

Volatile organic compounds are usually separated first with Gas Chromatography then ionized by electron impact (EI). Nonvolatile organic compounds are typically separated first with Liquid Chromatography then ionized with electrospray (ESI) or atmospheric pressure (APCI or APPI). Metals are usually ionized using Induced Coupled Plasma (ICP) at 5,000-6,000 K.

ASET currently has six operational mass spectrometers, interfaced to either a GC, LC, or standalone.

Connected to a Gas Chromatograph:

Agilent 5973N MSD Single Quadrupole (connected to Agilent headspace 6890 GC)

Agilent 5973N MSD Single Quadrupole (connected to Agilent autosampler 6890 GC)

Varian Saturn 2200 Ion Trap (connected to Varian CP 3800)

Connected to a Liquid Chromatograph:

Agilent 6410B triple quadrupole (connected to Agilent 1200 HPLC-DAD)

Agilent 6330 ion trap (connected to Agilent 1200 HPLC-VWD)


            Agilent 7500c ICP-MS